Optogenetic/Electrical Stimulation Systems
Pinnacle offers a turn-key system that can be used for optogenetics or electrical stimulation. Our systems use a stimulus controller module to control the frequency, duration, and intensity of stimulation events. When used for optogenetics, the stimulus controller drives headstage-mounted LED probes through our low-cost electrical commutator (no optical commutator or fibers are required). The same system can be used to apply electrical stimulation with the addition of an electrical isolator (Digitimer DS4 or similar).
Stimulation systems can be combined with simultaneous biopotential, neurotransmitter, or behavioral recordings to expand the range of experiments that can be performed with a single system setup. Existing Pinnacle users can easily add the stimulus controller to existing 8400 tethered setups to incorporate stimulation in their own experiments.
Click on the video below to see our system in action as optogenetic stimulation triggers a seizure event, in vivo, in a transgenic mouse.
The Stimulus Controller offers precise control of optical or electrical stimulation duration and intensity for both continuous and cyclical events.
Our 8401-HR data conditioning and acquisition system (DCAS) performs secondary amplification and filtering before sending data to Pinnacle's SIRENIA Acquisition software of collection via USB.
A low-torque commutator allows unencumbered movement for mice. Since Pinnacle systems power the light source through the preamplifier, no optical commutator is needed.
Our headstages amplify and filter the signal at the head of the animal to deliver clean, artifact-free data.
Prefabricated headmounts reduce surgery time and allow precise, reproducible electrode placement. Available headmounts include ready-to-insert EMG leads with a variety of different EMG placement options.
An optional, SYNCHRONIZED VIDEO SYSTEM is available.
Optogenetics Stimulation Systems >
Optogenetic Stimulation Systems are sold in 3 kits.
Hardware Kits
Includes all essential system components except the headstage. Learn more on the hardware tab below.
Headstage Kits
Includes the headstage configuration of your choice, along with the necessary EEG/biosensor-related surgical and testing supplies you need to get started. Learn more on the headstages tab below.
Optogenetics Accessory Kit
Includes optogenetic-specific surgical and testing equipment. Learn more on the hardware tab below.
Electrical Stimulation Systems >
Electrical Stimulation Systems are sold in 2 kits.
Hardware Kits
Includes all essential system components except the headstage. Learn more on the hardware tab below.
Headstage Kits
Includes the headstage configuration of your choice, along with the necessary EEG/biosensor-related surgical and testing supplies you need to get started. Learn more on the headstages tab below.
SUPPORTING PRODUCTS >
Synchronized Video
Integrated video recording provides a platform for synchronizing EEG and EMG changes with observable behavioral states. Video can be added to any new or existing hardware system. Captured video is displayed live on screen as it is streamed from the animal and is synchronized with other recorded data in playback mode. Learn more
Biosensors
Pinnacle's biosensors can be integrated with EEG and EMG recording using our four-channel system. Biosensor recording allows researchers to directly monitor second-by-second concentration changes in specific CNS analytes within a small brain region. Integrate with EEG recording to visualize and correlate these analyte changes with specific EEG activity. Learn more
Accelerometers
Pinnacle's accelerometer preamplifiers allow researchers to characterize locomotor behaviors with changes in neuronal activity. Correlate EEG measurements with behaviors such as stereotypies, reaction times, grooming, rearing and more. These preamplifiers are ideal for measuring small changes in movement (+/- 2 g) with high temporal resolution (max 500 Hz). Learn more
Sleep Deprivation
Pinnacle's automated sleep deprivation and fragmentation system uses a rotating metal bar to gently sleep deprive mice and rats without direct human intervention. It can be programmed to recognize real-time EEG/EMG activity and trigger bar rotation in response to sleep state. Learn more
