ENZYME-MODIFIED CARBON FIBER ELECTRODES (EM-CFEs) are designed to monitor real-time, sub-second, changes in concentration of multiple analytes using a single electrode. Glucose oxidase or lactate oxidase is entrapped in a hydrogel matrix, allowing for the simultaneous detection of non-electroactive metabolite (glucose and lactate) and an electroactive neurotransmitter (dopamine) via Fast Scan Cyclic Voltammetry (FSCV).
7 µm EM-CFE: SIMULTANEOUSLY MONITOR DOPAMINE WITH GLUCOSE OR LACTATE
| EM-CFE SPECIFICATIONS | ||
| Electrode Diameter | 7 µm | |
| Active Area Length | ~100 µm | |
| Glucose Linear Range | 0.05 to 2mM | |
| Lactate Linear Range | ~ 400 μM | |
| Pulled Capillary Electrode (includes connector wire) | ||
| For use in brain slices, anesthetized studies, or in vivo | ||
EM-CFEs can be used in brain slices, anesthetized studies, or in vivo for the real-time detection of dopamine and glucose with minimal tissue damage and subsecond response time.
| 7 µm ENZYME-MODIFIED CFE | ||
| Product | Kit # | |
| 7 µm EM-CFE for In Vitro, Brain Slices |
7017-L-Glucose
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| 7 µm EM-CFE (Wireless) for Freely Moving In Vivo |
7017-S-Glucose
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| 7 µm EM-CFE - No Connector |
7018-Glucose
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| 7 µm EM-CFE for In Vitro, Brain Slices |
7017-L-Lactate
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| 7 µm EM-CFE (Wireless) for Freely Moving In Vivo |
7017-S-Lactate
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| 7 µm EM-CFE - No Connector |
7018-Lactate
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Pinnacle offers a variety of biosensor recording systems for both in vivo and in vitro use. Solutions include wireless rat systems for recording up to three biosensors simultaneously. Tethered systems for mice and rats enable monitoring of two biosensors. In addition, we offer bench-top systems that support a range of studies, including brain slices, in vitro, and anesthetized animal experiments.
Pinnacle’s carbon fiber sensors have been optimized for fast scan cyclic voltammetry (FSCV) applications. Our FSCV system is robust, turn-key, and specifically designed to simplify the measurement of catecholamines. Tethered systems for mice and wireless systems for rats are available.
