Pinnacle’s tethered 8400 EEG/EMG MOUSE SYSTEM provides researchers the ability to configure and record four channels of EEG, EMG and biosensor data simultaneously. The combined system creates an exciting and powerful tool to obtain changes in neurocompound concentration in the brains of freely moving mice during sleep, seizure, and behavioral studies.
The tethered system employs a HEAD MOUNTED PREAMPLIFIER (#8406) that amplifies and filters biopotential signals and applies a bias across biosensors. Signals are then passed through the low torque MOUSE COMMUTATOR (#8408) to the 8401 Data Conditioning and Acquisition System (DCAS) for final stage conditioning and filtering. The 8401 DCAS interfaces with Pinnacle’s free acquisition software on a Windows based PC via USB.
The flexibility of the 8400 system allows user to change channel configurations by the simple swapping of preamplifiers (i.e. 2EEG/1EMG/1Biosensor for 1 EEG/1EMG/2Biosensors). Standard configurations are available for purchase (see below).
For complete system specifications, refer to the 8401 DCAS specifications along with the appropriate preamplifier specifications below.
Stereotaxically placed guide cannulas allow for insertion of biosensor(s) post-surgery. Pinnacle provides pre-fabricated head-mounts and recording electrodes for fast reproducible surgeries.
Headmounted 100X preamplifiers are the key to quality artifact-free data and house connections dock(s) for biosensor(s). Connections are made via friction fitting pins.
Low-torque commutators allow for unencumbered freedom of movement.
The 8401 DCAS performs secondary amplification filtering & conditioning; interfacing with a PC via USB.
An optimal, SYNCHRONIZED VIDEO SYSTEM is available to enable simultaneous correlation of behavioral and biosensor recordings.
Pinnacle’s SIRENIA™ acquisition & review software is FREE of charge. Advanced comprehensive analysis packages will be available for purchase in the future. Data can be exported as .EDF format.
• 8400-K1-SL 2 EEG/1 EMG/1 BIO FOR SLEEP
• 8400-K1-SE 2 EEG/1 EMG/1 BIO FOR SEIZURE
• 8400-K1-SE3 3 EEG/1 BIO FOR SEIZURE
• 8400-K1-SL-2BIO 1 EEG/1 EMG/2 BIO FOR SLEEP
• 8400-K1-SE-2BIO 1 EEG/1 EMG/2 BIO FOR SEIZURE
CONTENTS
• 8401 4-Channel Data conditioning & acquisition system
• 8406 Mouse preamplifier
• 8408 Mouse commutator/swivel with 18” mounting plate
Also included: cables for one animal, software and manuals
• SL SYSTEM FOR SLEEP
2 CHANNELS EEG (GAIN x100): HIGH PASS FILTERS: 0.5Hz
1 CHANNEL EMG (GAIN x100): HIGH PASS FILTERS: 10Hz
1 CHANNEL BIO
• SE SYSTEM FOR SEIZURE
2 CHANNELS EEG (GAIN x100): HIGH PASS FILTERS: 1.0Hz
1 CHANNEL EMG (GAIN x100): HIGH PASS FILTERS: 10Hz
1 CHANNEL BIO
• SE3 SYSTEM FOR SEIZURE
3 CHANNELS EEG (GAIN x100): HIGH PASS FILTERS: 1.0Hz
1 CHANNEL BIO
• SL-2BIO SYSTEM FOR SLEEP
1 CHANNEL EEG (GAIN x100): HIGH PASS FILTERS: 0.5Hz
1 CHANNEL EMG (GAIN x100): HIGH PASS FILTERS: 10Hz
2 CHANNELS BIO
• SL-2BIO SYSTEM FOR SEIZURE
1 CHANNEL EEG (GAIN x100): HIGH PASS FILTERS: 0.5Hz
1 CHANNEL EMG (GAIN x100): HIGH PASS FILTERS: 10Hz
2 CHANNELS BIO
• 4 CHANNELS (each configurable for AC or DC inputs)
• 14-bit resolution
• USER SELECTABLE GAIN 5,000 - 100,000 V/V
• ADJUSTABLE SAMPLING RATES (125 - 2,000 HZ)
• SOFTWARE CONFIGURABLE LOW PASS FILTERS 10 HZ - 1 KHZ
• HIGH PASS FILTERS: 0.5 Hz EEG, 10 Hz EMG for Sleep; 1.0 Hz EEG, 10 Hz EMG for Seizure
- 2 EEG/1 EMG/1 BIO FOR SLEEP OR SEIZURE
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Pinnacle offers 0.10” screws with wire leads attached for use with the 8-pin connector (#8415).
0.10” stainless steel bone screws to act as an anchor for the 8402 head mounts and guide cannula(s). It is recommended to utilize 1-2 screws (depending on surgery type) to securely affix the head mount and guide cannula(s).
Prefabricated EEG/EMG/Bio head mounts (#8402) come with EMG wires attached and act as a platform to connect cortical EEG electrodes. Head mounts are affixed to the skull via dental acrylic and weigh approximately 0.2 grams.
Stereotaxically placed guide cannulas allow for insertion of biosensors post-surgery. For single or dual biosensor implantations in mice the BASi mouse guide cannula (#7032) is recommended for use. The 7032 guide cannula shaft is 5 mm in length and approximately 600 M in diameter. The smaller size of the cannula allows for contralateral implantation of biosensors at a minimum distance of approximately 3.2 mm Pinnacle’s 7004 standard biosensor electrodes are compatible with the BASi mouse guide cannula. Guide cannulas are not reusable.2 EEG/1 EMG/1 BIO ACCESSORY KIT: FOR SLEEP OR SEIZUREPinnacle offers accessory kits for purchase that include all accesories necessary to complete setup as well as components needed for six surgeries. All quantities are (1) unless otherwise noted by a (#) after the product description.
8400-K3-SL/SE 2 EEG/1 EMG/1 BIO for sleep or seizure8402: EEG/EMG/BIO headmount (6)
8403: 0.10” screw with wire lead (18)
8249: Test source
8254: 23-gauge needle (6)
7035-M: Probe holder for mouse cannula
8209: Pkg of eight 0.10” screws
7032: BASi mouse cannula (6)
8134: Test load (2)
9005: 4-Port powered USB hub
8249-M: Mouse BASi stylet ground
8241-F: Screwdriver for EEG screws
8255: Multimeter
- 1 EEG/1 EMG/2 bio for sleep or seizure
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Pinnacle offers 0.10” screws with wire leads attached for use with the 8-pin connector (#8415).
Pinnacle offers 0.10” stainless steel bone screws to act as an anchor for the 8235-SM head mounts and guide cannula. It is recommended to utilize 1-2 screws to securely affix the head mount and guide cannula.
A 6-PIN connector (#8235-SM) is used in place of the pre-fabricated headmount for 3 EEG recordings. The pins are bent at a 90o angle for accessible soldering. Pinnacle’s 0.10” screws with wire lead (#8403) or depth electrodes can be wired to the 6-PIN connector.
Stereotaxically placed guide cannulas allow for insertion of biosensors post-surgery. For single or dual biosensor implantations in mice the BASi mouse guide cannula (#7032) is recommended for use. The 7032 guide cannula shaft is 5 mm in length and approximately 600 mm in diameter. The smaller size of the cannula allows for contralateral implantation of biosensors at a minimum distance of approximately 3.2 mm Pinnacle’s 7004 standard biosensor electrodes are compatible with the BASi mouse guide cannula. Guide cannulas are not reusable.1 EEG/ 1 EMG/ 2 BIO ACCESSORY KIT: FOR SLEEP OR SEIZUREPinnacle offers accessory kits for purchase that include all accesories necessary to complete setup as well as components needed for four surgeries. All quantities are (1) unless otherwise noted by a (#) after the product description.
8400-K3-SL/SE 2 EEG/1 EMG/1 BIO for sleep or seizure8402: EEG/EMG/BIO headmount (6)
8403: 0.10” screws with wire leads (16)
8249: Test source
8254: 23-gauge needle (6)
7035-M: Probe holder for mouse cannula
8209: Pkg of eight 0.10" screws
7032: BASi mouse cannula (12)
8134: Test load (2)
9005: 4-Port powered USB hub
8249-M: Mouse BASi stylet ground
8241-F: Screwdriver for EEG screws
8255: Multimeter